IUI full form is Intrauterine Insemination otherwise also known as Artificial insemination, is a procedure under which washed out sperms are introduced into the uterus of the woman during her ovulation hoping that the sperms will then travel to the fallopian tube to fertilize the released eggs.
IUI procedure is recommended by doctors as a first line of treatment for unexplained infertility, when all the factors of fertility are strong and yet the couple is unable to conceive. IUI as a procedure is a very simple one and takes under 20 minutes to go through without any need of sedation. It's a painless procedure that does not need one to take pain medication and also, it's less invasive in nature hence the side effects are almost nil. The success rate of the procedure is around 10-20% and by the third attempt it will be around 60% which helps in increasing the chance of conceiving.
The procedure is comparatively cheaper than other aided fertility procedures like IVF and may cost anywhere between 10,000 to 40,000 depending on the number of attempts and the type of fertility clinic.
Giving birth to a child and the entire process of it is the most beautiful phase in a woman's life. If you have been planning to have a child and tried but failed at conceiving, there could be many different reasons that might have caused an obstacle. In such cases most people choose for an aided or medically assisted procedure for pregnancy. IUI is one such simple yet effective procedure that helps a couple conceive when it doesn't otherwise happen naturally
IUI can be a choice in one or more of the following conditions as listed below:
Donor sperm: When a woman needs a donor sperm to get pregnant in case of single parenting or due to infertility of the partner then IUI is the best available option.
Semen Allergy: Semen consists of non-sperm parts as well and some women have an allergy towards it. In any allergic reaction the immune response of the body is to create antibodies against the said allergen and kill it. So, in the case of semen allergy the body responds by killing the semen containing the sperms as well, leading to infertility. In IUI the non-sperm part is removed and only the normal and high-quality sperms are injected directly into the uterus to increase the chances of conception. A semen allergy can be detected when a woman has allergic reactions after unprotected sex like burning in vagina after sex, change in skin color or area color after contact with semen, swelling of external genitalia. Surprisingly there are no such symptoms when protected sex happens, this helps with diagnosing semen allergy and a couple of tests called skin prick test and allergen specific - Ige is used to confirm the diagnosis.
Unexplained infertility: Unexplained infertility is when the standard fertility tests failed to determine what was the exact cause for the failure of the couple to get pregnant. In cases of unexplained infertility IUI becomes the first step of treatment.
Partial infertility in men: Partial infertility is having conditions like low sperm motility or abnormal structure of the sperms, in such cases IUI seems like the best option because here the collected sample is tested and only the normal and high-quality ones are picked up for insemination.
Endometriosis: Endometriosis is a condition where a tissue like the one that lines the surface of the uterus starts growing elsewhere especially in fallopian tubes and over the ovary. The nature of the endometrium is that it sheds in every menstrual cycle and so wherever the tissue is present the same scenario occurs. Endometriosis can then cause infertility by scarring the fallopian tube layer or altering the structure of the egg or by creating inflammation and hormonal imbalance. In women with mild endometriosis and normal structure of the fallopian tubes, then with aid of medication ovulation is triggered and IUI procedure is carried out. To treat infertility arising due to endometriosis IUI may seem to be the easiest, most beneficial procedure to aid in conception.
Cervical related infertility: The cervix is an organ that connects external genitalia to the vagina and the cervix releases mucus in order to keep the inside smooth. In some cases, the mucus released is so thick that it forms a plug not allowing the sperm to pass through it leading to infertility. In such conditions IUI will help since during the procedure the sperms are introduced directly into the uterus.
Vaginal issues: Vaginismus and increased vaginal pH can be one of the few reasons leading to infertility. In vaginismus the vaginal wall may contract so much that it won’t allow the penis to pass through leading to infertility. The normal vaginal pH is between 3.8 to 5.0 making it acidic, in order to prevent infections. Sometimes this might lower even further causing infertility as it may kill the sperms passing through it, acting as a spermicide. In such conditions IUI may help by directly introducing the sperms into the uterus.
Erectile dysfunction: Erectile dysfunction can be an indirect cause of infertility. In such conditions usually the sperm count, or sperm motility are unaffected. Hence using IUI in such conditions will help the couple conceive normally
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IUI treatment cost in India can range between Rs. 10400 to Rs. 19200, average cost of IUI in India is around Rs. 14000, this may depend on various factors like your age, number of cycles, medicines and many other factors. The typical cost of IUI in India varies depending on where you live, IVF center chosen by you. However, the cost of the IUI treatment in India should not be the only consideration in your budget. A single cycle of fertility treatment is not usually sufficient to conceive. A successful pregnancy can take up to three cycles for many couples in India. As a result, you should include the cost of additional cycles required to make it a success in India. If you're having the surgery done somewhere else, you'll have to factor in travel and lodging charges as well.
|IUF Treatment Cost||Average Price||Price|
|Agra||14000||₹13100 - ₹16100|
|Agra||13500||₹11100 - ₹16100|
|Ahmedabad||12500||₹10100 - ₹15100|
|Ajmer||11000||₹10100 - ₹12100|
|Akola||11000||₹10100 - ₹12100|
|Aligarh||11000||₹10100 - ₹12100|
|Allahabad||14500||₹13100 - ₹16100|
|Alwar||11000||₹10100 - ₹12100|
|Amritsar||14500||₹13100 - ₹16100|
|Aurangabad||14500||₹13100 - ₹16100|
|Aurangabad||19000||₹12100 - ₹17100|
|Bangalore||12500||₹10100 - ₹15100|
|Bhopal||14500||₹12100 - ₹17100|
|Chandigarh||14000||₹12100 - ₹16100|
|Chennai||16500||₹14100 - ₹19100|
|Coimbatore||12000||₹10100 - ₹14100|
|Cuttack||11000||₹10100 - ₹12100|
|Dehradun||11000||₹10100 - ₹12100|
|Faridabad||13500||₹11100 - ₹16100|
|Ghaziabad||15000||₹12100 - ₹19100|
|Gorakhpur||11000||₹10100 - ₹12100|
|Gurgaon||125000||₹10100 - ₹15100|
|Guwahati||11000||₹10100 - ₹12100|
|Hisar||11000||₹10100 - ₹12100|
|Hubli||11000||₹10100 - ₹12100|
|Hyderabad||12500||₹10100 - ₹15100|
|Indore||12000||₹11100 - ₹13100|
|Jaipur||11500||₹8000 - ₹15100|
|Jalandhar||11000||₹10100 - ₹12100|
|Jalgaon||11000||₹10100 - ₹12100|
|Jammu||11000||₹10100 - ₹12100|
|Kanpur||13000||₹11100 - ₹15100|
|Kolkata||14500||₹12100 - ₹17100|
|Lucknow||14000||₹13100 - ₹15100|
|Ludhiana||14500||₹13100 - ₹16100|
|Ludhiana||12500||₹10100 - ₹15100|
|Madurai||14000||₹13100 - ₹16100|
|Mangalore||11000||₹10100 - ₹12100|
|Mumbai||13500||₹11100 - ₹16100|
|Mysore||13000||₹12100 - ₹15100|
|Nagpur||14000||₹12100 - ₹16100|
|Nashik||14500||₹13100 - ₹16100|
|Nashik||14000||₹12100 - ₹16100|
|New-delhi||13500||₹11100 - ₹16100|
|Noida||19000||₹19100 - ₹20200|
|Patna||12500||₹10100 - ₹15100|
|Pondicherry||13000||₹12100 - ₹15100|
|Pune||13500||₹11100 - ₹16100|
|Ranchi||14500||₹13100 - ₹16100|
|Rohtak||11000||₹10100 - ₹12100|
|Secunderabad||11000||₹10100 - ₹12100|
|Siliguri||14500||₹13100 - ₹16100|
|Surat||11500||₹10100 - ₹13100|
|Tirunelveli||11000||₹10100 - ₹12100|
|Trichy||11000||₹10100 - ₹12100|
|Vadodara||14500||₹13100 - ₹16100|
|Vadodara||11500||₹10100 - ₹13100|
|Varanasi||14500||₹13100 - ₹16100|
|Vellore||11000||₹10100 - ₹12100|
|Vijayawada||11000||₹10100 - ₹12100|
|Visakhapatnam||14500||₹12100 - ₹17100|
|Warangal||11000||₹10100 - ₹12100|
Updated On 01-07-2022
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IUI procedure recommended for couples with unexplained infertility, partial infertility in male or in cases with cervical causes of infertility. This procedure aims at giving a head start for the sperms to be able to get a chance to fertilize the egg by entering the womb. It gives the couple who are physically vulnerable for reproduction due to factors like age and hormonal issues a chance at parenthood.
IUI Success rate for getting pregnant in women is around 10-20% during each cycle of IUI. The more the cycles one goes through the higher are the chances of getting pregnant. The odds of conceiving rises by 10-20% with each attempt and hence by the third attempt it can be around 40-60%. The chances are greater in women below 35 years of age.
Ideally the conception can take place within 2 days after IUI procedure, and the implantation might take another 12 days and 2-3 days are needed to build up the hCG levels. Which means anywhere between 14 - 16 days after IUI you can take a pregnancy test to find out if you have conceived.
The IUI process is very simple, and it takes not more than 10-15 minutes to finish. IUI procedure doesn’t need a separate operation theatre or a sophisticated set up and can be done in the doctor’s clinic itself. IUI is a painless procedure, and you don't need any pain medication or anesthesia to undergo the procedure.
The tests preceding IUI are done only to check if the tubes are clear, and that the ovulation has occurred in women and in men it includes testing sperm count and getting the sample ready.
The final IUI procedure step by step happens in the following sequence:
The IUI procedure is usually performed anywhere between 6-8 hours after ovulation and a bed rest of 10 minutes is recommended after the procedure to ensure better success rate.
In order for the IUI procedure to be successful there should be more than 5 million normal and high-quality sperms. During the IUI process, around 0.2 to 0.5ml of the sample is introduced into the uterus.
IUI procedure is a relatively simple process and the associated risks of it, if any, are very low and are not very serious. By any chance there might however be some symptoms arising after IUI treatment which are as following
Infection: There are slight chances of getting infection due to the procedure since it involves insertion of a tube and speculum and since it's mildly invasive in nature.
Spotting: Since the IUI procedure includes inserting a catheter into the uterus there may be a slight bleeding from the vaginal wall but don’t worry this will have no effect on the conception
Multiple pregnancies: IUI treatment in itself may not lead to multiple pregnancies but if it is done when the woman is using medicines for ovulation then there are chances of twin or triplet birthing.
Headache: In case a woman is on medication to increase ovulation for the IUI procedure than as a side effect the medicines may cause headache.
Weight gain: In case the woman is taking medication for increasing ovulation for the IUI procedure the medication may cause weight gain which could be around 3kgs.
Shortness of breath: Sometimes a woman is required to take medication to induce ovulation at the time of IUI process leading to shortness of breath as a side effect of the medication.
Severe abdominal or pelvic pain: Although IUI procedure won't directly cause any issue, if one is taking medication to induce ovulation for IUI procedure it may lead to abdominal and pelvic pain.
The success rate of IUI depends on various factors for different couples and with each attempt the success rate can increase by 10-20% meaning by the end of the third attempt the chances of conception are high. However, it also depends on the age of the woman, underlying conditions leading to infertility etc to determine the success rate of the IUI procedure.
Other factors also include the drugs used to get fertile and if any other medications are used for problems like psychosis and depression etc.
Ideally the success reduces manifold in women who are 40 or above.
You can discuss the success rate of the procedure with your physician to choose better options if needed.
The chances of success of IUI treatment is 10-20% and it increases by the same percentage with every attempt. However, there are ways by which you can improve the chances of the IUI working successfully by taking some precautions on your end.
Avoid stress since stress is considered to be a major factor contributing to infertility issues. It's important that you stay calm all the way through the process.
Avoiding ejaculation for three days until the day your partner must donate sperm for the procedure helps improve the success rate of IUI treatment since the volume of semen and the amount of sperm matter a lot during the IUI procedure. The sperm has life until five days so waiting for three days until the procedure is ideal as there will be an increased semen volume and sperm count. But abstaining beyond 5 days will have a negative impact.
Eat healthy and nutritious meals as they are associated not only with improving fertility but also they contribute in improving the overall well being of a person.
Exercising regularly helps keep you in shape and can also aid in improving fertility. But it's important to not indulge in strenuous exercises as they may have a negative effect. A long walk, a quick jog and a few minutes of yoga daily can prove to be very beneficial.
A good 3 attempts of IUI procedure and keeping in mind all the above tips will help you have a successful conception. In case the attempts fail after 3 times, further tests and other treatment options can be considered.
IVF (in vitro fertilization) and IUI are the most common procedures used to treat infertility. Both of them are the most popular procedures amongst couples who have not been able to conceive naturally due to various physical or hormonal barriers. However, both the procedures are different from each other.
In IUI treatment, washed out sperms are inserted into the uterus directly hoping that it would travel to the fallopian tubes and fertilize the egg. It's a simple procedure that requires no prior medication or anesthesia and also does not require getting admitted into hospital or an operation theater. It's a quick 20 minute procedure and isn't very complicated.
IVF on the other hand requires a lot of time and is also a costlier procedure as compared to IUI and it requires to carry out a set of investigations before the procedure begins. In IUI it's rare to give medicine to stimulate ovulation but in IVF FSH injections are given to specifically help release multiple eggs as opposed to one which is normal. These matured eggs present in the ovarian follicles are then collected in a procedure called egg retrieval where there is a slight sedation given to the patient. Using an ultrasound guide the probe which has a needle attached on top is passed through vagina into the ovarian follicles to retrieve the fluid. The fluid is then studied under a microscope to look for the eggs. The entire procedure takes about 20-30 minutes after which a bed rest for an hour is suggested. Around the same time semen sample is collected from your partner as well. The semen sample is washed out and is mixed with the collected eggs after 4 hours of retrieval and kept in an incubator overnight and observed the next day for fertilization. About 60-70% of them usually become fertilized and the fertilized eggs are kept under incubator for another 48 hours. After around 4-5 days from egg retrieval a single or multiple good quality embryos are implanted based on the medical conditions of the mother.
The embryo is implanted using a tube and the egg is directly released into the uterus, which is a painless procedure, doesn't require sedation and takes place within a few minutes. The remaining embryos will be frozen in case the need for the same may arise later. In order to find out if the implantation was successful or not one needs to wait for 14-15 days before taking the pregnancy test.
As opposed to IUI treatment, IVF procedure takes a long duration and is more invasive. IUI is comparatively a more natural procedure and is far less invasive. Due to the medication involved the risk of side effects are higher in IVF as opposed to IUI. The chance of multiple pregnancy is more in IVF in case multiple embryos were implanted and in IUI the same is low in case there were no medications involved to induce ovulation.
In the traditional method of conception, the sperms are required to travel from vagina into the fallopian tube in order to fertilize the egg released by the ovary. In case of IUI, this process is a bit simplified as the best quality sperms are directly introduced into the uterus where the length of the travel for the sperm is reduced. The chances of conception are increased by 7-10% as opposed to traditional methods of conception.
Actually, there is no difference in terms of the child conceived via a traditional method of conception vs that in IUI. The only difference is in IUI the process was medically aided whereas in the traditional method it wasn't. That being said, in either case the health of the baby depends completely on the wellbeing of the parents and the egg formed.
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